History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines
Identifieur interne : 000445 ( Main/Exploration ); précédent : 000444; suivant : 000446History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines
Auteurs : I. Barberis [Italie] ; P. Myles [Royaume-Uni] ; S. K. Ault [États-Unis] ; N. L. Bragazzi [Italie] ; M. Martini [Italie]Source :
- Journal of Preventive Medicine and Hygiene [ 1121-2233 ] ; 2016.
Abstract
Influenza is a highly infectious airborne disease with an important epidemiological and societal burden; annual epidemics and pandemics have occurred since ancient times, causing tens of millions of deaths. A hundred years after this virus was first isolated, influenza vaccines are an important influenza prevention strategy and the preparations used display good safety and tolerability profiles. Innovative tools, such as recombinant technologies and intra-dermal devices, are currently being investigated in order to improve the immunological response. The recurring mutations of influenza strains has prompted the recent introduction of a quadrivalent inactivated vaccine. In the near future, scientific research will strive to produce a long-lasting universal vaccine containing an antigen that will offer protection against all influenza virus strains.
Url:
PubMed: 27980374
PubMed Central: 5139605
Affiliations:
- Italie, Royaume-Uni, États-Unis
- Angleterre, Maryland, Nottinghamshire
- College Park (Maryland), Nottingham
- Université de Nottingham, Université du Maryland
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><title>Summary</title>
<p>Influenza is a highly infectious airborne disease with an important epidemiological and societal burden; annual epidemics and pandemics have occurred since ancient times, causing tens of millions of deaths. A hundred years after this virus was first isolated, influenza vaccines are an important influenza prevention strategy and the preparations used display good safety and tolerability profiles. Innovative tools, such as recombinant technologies and intra-dermal devices, are currently being investigated in order to improve the immunological response. The recurring mutations of influenza strains has prompted the recent introduction of a quadrivalent inactivated vaccine. In the near future, scientific research will strive to produce a long-lasting universal vaccine containing an antigen that will offer protection against all influenza virus strains.</p>
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<region><li>Angleterre</li>
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